Webb1 jan. 2024 · Tiam1 (T-lymphoma invasion and metastasis) has been identified as a specific activator of the Rho-like GTPase Rac (Rho family proteins, GTPase) and is … WebbTIAM1-201 ENSP00000286827 ENST00000286827: Q13009 [Direct mapping] T-lymphoma invasion and metastasis-inducing protein 1 A0A2X0TW27 [Target identity:100%; Query …
TIAM1 TIAM Rac1 associated GEF 1 [ Homo sapiens (human) ]
Webb3 mars 2024 · We identified that TIAM1, the guanine nucleotide exchange factor, is a target of YAP1-TEAD4 complex. YAP1 promotes TEAD4 binding to the enhancer region of TIAM1, which activates TIAM1 expression and subsequently increases RAC1 activity. Webbthat TIAM1 expression is associated with lung fibroblast differentiation in pulmonary fibrosis via an NF‑κB‑dependent pathway, and that TIAM1 inhibits lung fibroblast differentia-tion in pulmonary fibrosis. Introduction Human T‑lymphoma invasion and metastasis‑inducing protein 1 (TIAM1) is 1,591 amino acids long with a molecular ontario midland railroad map
The Rac Exchange Factor Tiam1 Is Required for the Establishment …
Webb24 dec. 2024 · TIAM1 is overexpressed in colorectal cancer (CRC) tumors from patients who did not respond to chemotherapeutic drugs and levels of TIAM1 expression served … Webb1 aug. 2008 · Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells. Minard ME et al: 15735692: 2005: The guanine nucleotide exchange factor Tiam1 increases colon carcinoma growth at metastatic sites in an orthotopic nude mouse model. Minard ME et al: 14999151: 2004: Webb16 okt. 2024 · Here, we show that Tiam1, a Rac1-specific guanine nucleotide exchange factor (GEF) that was previously identified as a critical mediator of NMDAR-dependent dendritic spine development, is activated in the ACC in chronic pain mice displaying depressive-like behaviors. ontario mid hiking boot