WebAntibodies that recognize cancer biomarkers, such as MUC16, can be used as vehicles to deliver contrast agents (imaging) or cytotoxic payloads (therapy) to the site of tumors. MUC16 is overexpressed in 80% of epithelial ovarian cancer (EOC) and 65% of pancreatic ductal adenocarcinomas (PDAC), where effective ‘theranostic’ probes are … WebApr 19, 2011 · The panel of ovarian tumor cell lines used consisted of OVCAR2, OVCAR3, OVCAR4, OVCAR5, OVCAR10, A2780, CP70, C30, PEO1, PEO4, SKOV3, and UPN251 , , . All tumor cells were cultured in RPMI 1640 medium supplemented with 10% FBS, 0.3 U/mL insulin, 2 mM L-glutamine, 100 U/mL penicillin, and 100 µg/mL streptomycin.
Differential Expressions of Adhesive Molecules and Proteases
WebOvarian cancer cells had high level of cleaved caspase-6 and cleaved lamin A/C. b Immunochemoluminescence blot showing the expression of lamin A/C and active caspase-6 in human primary surface ... WebA cell line, NIH:OVCAR-3, has been established from the malignant ascites of a patient with progressive adenocarcinoma of the ovary after combination chemotherapy with … bmo investorline active trader
Abstract 2153: Cyclin E1 protein overexpression sensitizes ovarian …
WebSep 16, 2024 · The invention provides B7-H3 targeting fusion proteins and methods of use thereof. The targeting fusion proteins include B7-H3 targeting tri-specific killer engager molecules comprising a B7-H3 targeting binding protein, a CD16 targeting binding protein, and an interleukin-15 protein. The methods of use thereof include methods of treating … WebMar 1, 2005 · OVCAR2 and PEO4 cells were pretreated with 50 μ M AG490 followed by treatment with a range of platinum concentrations. AMD473 sensitivity was enhanced 4.1-fold in PEO4 cells ( P =0.001) and 9.1-fold in OVCAR2 cells ( … WebInvitrogen Anti-NOTCH3 Polyclonal, Catalog # PA5-89283. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This antibody reacts with Human, Mouse, Rat samples. Supplied as 100 µL purified antibody (1.35 mg/mL). bmo investorline advice direct login