WebTranslations in context of "Health Canada has used" in English-French from Reverso Context: Health Canada has used this funding to develop a guidance document that should accelerate access to available pandemic drugs. Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication, which is presently rarely used. In the past, it was widely used for a variety of indications, including pregnancy support for those with a history of recurrent miscarriage, hormone therapy for menopausal … See more DES has been used in the past for the following indications: • Recurrent miscarriage in pregnancy • Menopausal hormone therapy for the treatment of menopausal symptoms such as hot flashes See more At more than 1 mg/day, DES is associated with high rates of side effects including nausea, vomiting, abdominal discomfort, headache, and bloating (incidence of 15–50%). See more DES belongs to the stilbestrol (4,4'-dihydroxystilbene) group of compounds. It is a nonsteroidal open-ring analogue of the steroidal estrogen estradiol. DES can be prepared from anethole, which also happens to be weakly estrogenic. Anethole was See more Alan Turing, the ground-breaking cryptographer, founder of computing science and programmable computers, who also proposed the actual theoretical model of biological morphogenesis See more DES has been assessed in the past in clinical studies at extremely high doses of as much as 1,500 to 5,000 mg/day. See more Pharmacodynamics Estrogenic activity DES is an estrogen; specifically, it is a highly potent full agonist of both of the estrogen receptors (ERs). It has approximately 468% and 295% of the affinity See more Synthesis DES was first synthesized in early 1938 by Leon Golberg, then a graduate student of Sir Robert Robinson at … See more
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WebMay 15, 2004 · Between 1938 and 1971, as many as 4 million women in the United States took diethylstilbestrol (DES), an oral synthetic non-steroidal estrogen, for the purpose … WebNov 17, 2015 · Diethylstilbestrol (DES) was used to reduce adverse pregnancy outcomes or as an anti-cancer reagent. In addition to these positive uses, the estrogenic effects of this compound can also induce several disorders and cancer in the fetus . ... Another article reported the concentration of D4 and its predicted dermal exposure in Canada ... WebFeb 28, 2024 · Diethylstilbestrol tablets, USP 0.5mg. FOR VETERINARY USE ONLY. Active Ingredient. Each tablet contains: 0.5 mg Diethylstilbestrol U.S.P. DIN 02433400. … knockout goldarm gulch