Webof outbred strain ddY). Some disease models have been devel-oped from the ddY strain, including HIGA mice (IgA nephritis model) and obese/diabetic mice ( 21, 22 ). Dietary … WebThe antipruritogenic effect of the 70% ethanol extract obtained from Kochiae Fructus (fruits of Kochia scoparia) and its active components were investigated on a compound 48/80-induced pruritogenic model in male ddY strain mice. The extract (200, 500 mg/kg, p.o.) inhibited the scratching behavior as a pruritogenic indicator.

ddY Mouse - an overview ScienceDirect Topics

WebThe inbred strain DDY was developed from the outbred "dd"; a stock originally bred in Germany and transferred to Japan before 1920. The strain name ddY stands for Deutschland, Denken, and Yoken. In Japan, ddY is used as a general purpose mouse; it is not known if traits attributed to ddY in the literature are found in the inbred … WebNational Center for Biotechnology Information domain force group policy update

The use of animal models in diabetes research - King - 2012 - Wiley

WebAbstract. By the selective breeding of obese male mice of the ddY strain and using indices of the heavy body weight and appearance of urinary glucose, we established two inbred strains in 1992: one with obesity and urinary glucose (Tsumura, Suzuki, Obese Diabetes: TSOD) and the other without them (Tsumura, Suzuki, Non Obesity: TSNO). WebThe ddY mouse strain is a well-characterized model of spontaneous IgAN, which develops glomerulonephritis and a remarkable deposition of IgA in the mesangium accompanied with codeposits of IgG, IgM, and C3 (Imai et al., 1985). However, the high degree of variability in the age of onset and severity of disease in this model presents a disadvantage. WebThe ddY strain is an outbred one, and has been maintained as a closed colony. Mice of the strain show good reproductive performance and superior growth. In Japan, this strain, … fake police round antennas