2024 Ddit4 and pancreatic cancer

Ddit4 and pancreatic cancer

Author: elmz

August undefined, 2024

WebSUMMARY TISSUE BRAIN SINGLE CELL TISSUE CELL PATHOLOGY DISEASE IMMUNE BLOOD SUBCELL CELL LINE STRUCTURE METABOLIC DDIT4 … WebMay 8, 2024 · DDIT4 gene encodes a protein whose main action is to inhibit mTOR under stress conditions whilst several in vitro studies indicate that its expression favors cancer progression. We have...

The m6A demethylase ALKBH5-mediated upregulation of DDIT4 …

WebApr 30, 2024 · DDIT4 Novel Mutations in Pancreatic Cancer. Fadian Ding Department of Surgery, 1st Affiliated Hospital, Fujian Medical University, 350004, China. Author profile Search articles by ORCID 0000-0002-9868-3094 Ding F1, Xiaoping Hong WebPrognostic marker in renal cancer (unfavorable), pancreatic cancer (unfavorable) and head and neck cancer (unfavorable) flashcard byjus

In silico evaluation of DNA Damage Inducible Transcript 4 gene (DDIT4 …

WebMar 17, 2024 · The phosphorylation level of mammalian target of rapamycin complex 1 (mTORC1) is regulated by DDIT4, 34 located at the core of multiple metabolic pathways, and it is a target for tumor treatment, 35 especially in the cancer exhibiting activated AKT/mTORC cascade. 36 Functional studies proved that DDIT4 inhibited mTORC1 by … WebJun 26, 2024 · Cancer cachexia is a multifactorial metabolic syndrome that causes up to 20% of cancer-related deaths. Muscle atrophy, the hallmark of cancer cachexia, … WebJun 9, 2024 · These genes included DNA-damage-inducible transcript 4 (DDIT4), sulfatase 1 (SULF1) as coding RNA genes and miR-181d-5p, miR-148b-3p and TPTE Pseudogene 1 (TPTEP1) as ncRNA genes. ... studies reported SULF1 as a tumor suppressor effector and its down-regulation levels related to several cancers such as … flashcard canva

High expression of DNA damage-inducible transcript 4 (DDIT4) is associ…

DDIT4 Novel Mutations in Pancreatic Cancer. - Abstract - Europe …

WebNational Center for Biotechnology Information WebSep 14, 2024 · Serum trypsin levels were significantly higher in both patients with pancreatic duct adenocarcinoma (PDAC) and pancreatitis compared with normal control values ( p < 0.0001 and p < 0.0001, respectively). These findings indicated the occurrence of pancreas damage in both pancreatitis and pancreatic cancer. flashcard captain kellyWebSep 24, 2024 · Besides, miR-496 could be sequestered by NNT-AS1 to elevate the expression of DNA damage inducible transcript 4 (DDIT4) in PCa. ... For instance, lncRNA HOTTIP facilitates cell proliferation and migration in pancreatic cancer . CUDR facilitates liver cancer stem cell growth via its regulation on the expression of TERT and … flashcard bread

"WebApr 30, 2024 · In this study, we found mutation in the 3′-UTR region of DDIT4, which may be associated with DDIT4 expression and tumor autophagy in pancreatic cancer tissues. … " - Ddit4 and pancreatic cancer

Ddit4 and pancreatic cancer

National Center for Biotechnology Information

WebJul 1, 2024 · Scientific Reports - High expression of DNA damage-inducible transcript 4 (DDIT4) is associated with advanced pathological features in the patients with colorectal … WebExpression of DDIT4 (Dig2, FLJ20500, REDD-1, REDD1, RTP801) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... PANCREATIC CANCER - Interactive survival scatter plot i & Survival analysis i. DDIT4 is prognostic, high expression is unfavorable in pancreatic cancer ...

Did you know?

Webmutations and the value of novel gene mutation in the DNA damage-inducible transcript 4 (DDIT4) and signaling pathway in pancreatic cancer. Polymerase chain reaction (PCR) was performed to amplify the DNA sequences of DDIT4 from patients with pancreatic ductal adenocarcinoma. In addition, we used IHC to detect the expression level of DDIT4 in ... WebMar 29, 2024 · Data show that DNA damage-inducible transcript 4 (DDIT4) was upregulated in gastric cancer (GC) cells and tissue, and that the mitogen-activated …

WebWe speculated that DDIT4 gene mutation may be involved in pancreatic cancer cell adapted to antitumor ther- apy and harsh microenvironment. Mechanistically, the gene … WebSep 23, 2024 · Results: Univariate and multivariate Cox regression analyses identified a 5-gene signature that contained CAV1, DDIT4, SLC40A1, SRXN1 and TFAP2C. The signature could efficaciously stratify PDAC patients with different recurrence-free survival (RFS), both in the training and validation cohorts.

WebPa ge 3/ 9 We speculate that DDIT4 plays an important role in pancreatic cancer, but its specics are still unknown. Then, we investigated the role of DDIT4 in pancreatic cancer through clinical ... WebNov 30, 2024 · A large study demonstrated that the combination of smoking, long-standing diabetes and a poor diet increases the risk of pancreatic cancer beyond the risk of any one of these factors alone. Complications …

WebSep 2, 2024 · The m6A demethylase ALKBH5-mediated upregulation of DDIT4-AS1 maintains pancreatic cancer stemness and suppresses chemosensitivity by activating … flash card burnerWebJul 15, 2016 · Results: DDIT4 had low structural alterations rates (0-5.1%); however, in breast tumors xenografts, gene amplification occurs in 17.4%, indicating a key role in tumor progression. High levels of DDIT4 was significantly associated with a worse outcome in breast cancer (n = 4142), P = 3×10-14 (HR = 1.64, CI95%: 1.44-1.87). flashcard carpet gameWebNational Center for Biotechnology Information flashcard cartoonWebSep 25, 2024 · Gene ID: 110806271, updated on 25-Sep-2024 Summary Other designations RP11-442H21.2 GeneRIFs: Gene References Into Functions The m (6)A demethylase ALKBH5-mediated upregulation of DDIT4-AS1 maintains pancreatic cancer stemness and suppresses chemosensitivity by activating the mTOR pathway. flash card ce2 anglaisWebSep 2, 2024 · The m 6 A demethylase ALKBH5-mediated upregulation of DDIT4-AS1 maintains pancreatic cancer stemness and suppresses chemosensitivity by activating the mTOR pathway. ... flashcard caseWebPhosphoinositide-3-kinase regulatory subunit 1 (PIK3R1) was identified as an oncogene in gastric cancer, breast cancer, and pancreatic cancer. 50–52 Furthermore, PIK3R1 was found to be involved in the pathogenesis of coronary artery disease. 53 Yan et al have demonstrated that PIK3R1 can induce the suppression of invasiveness in breast cancer ... flash card camcordersWebMay 3, 2024 · Polymerase chain reaction (PCR) was performed to amplify the DNA sequences of DDIT4 from patients with pancreatic ductal adenocarcinoma. In addition, … flashcard categories